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Image Search Results
Journal: Cells
Article Title: Comprehensive Multi-Omics Analysis Reveals Aberrant Metabolism of Epstein–Barr-Virus-Associated Gastric Carcinoma
doi: 10.3390/cells8101220
Figure Lengend Snippet: Principal component analysis (PCA) score plots of differences in transcriptome profiles ( a ) between AGS-Epstein–Barr-virus (EBV) and AGS and ( b ) gastric cancer tissue (GCT)-EBV and GCT. Both comparisons reveal clear separations caused by the association of EBV with gastric cancer.
Article Snippet: AGS is a human, female-origin,
Techniques:
Journal: Cells
Article Title: Comprehensive Multi-Omics Analysis Reveals Aberrant Metabolism of Epstein–Barr-Virus-Associated Gastric Carcinoma
doi: 10.3390/cells8101220
Figure Lengend Snippet: Metabolic profiles of AGS-EBV and AGS made using gas chromatography–mass spectrometry (GC-MS) and high-performance liquid chromatography coupled with triple quadrupole mass spectrometry (HPLC-QqQ MS). ( a ) Two-dimensional (2D) score plot derived using the untargeted GC-MS method showed a tendency of difference between the AGS-EBV and AGS cell lines. ( b ) The heatmap derived from GC-MS-based analysis showed a marked contrast in the expression of the detected metabolites between AGS-EBV and AGS. Also, the ( c ) 2D score plot derived from the HPLC-QqQ MS method and ( d ) heatmap also derived from the large-scale, targeted HPLC-QqQ MS method showed apparent differences between the AGS-EBV and AGS cell lines. ( e ) The pathway analysis based on polar metabolites differentially expressed between AGS-EBV and AGS suggests that 15 metabolic pathways are significantly ( p -value < 0.05, FDR < 0.1) associated with the effect of EBV infection on gastric cancer.
Article Snippet: AGS is a human, female-origin,
Techniques: Gas Chromatography, Mass Spectrometry, Gas Chromatography-Mass Spectrometry, High Performance Liquid Chromatography, Derivative Assay, Expressing, Infection
Journal: Cells
Article Title: Comprehensive Multi-Omics Analysis Reveals Aberrant Metabolism of Epstein–Barr-Virus-Associated Gastric Carcinoma
doi: 10.3390/cells8101220
Figure Lengend Snippet: Differential expression of lipids between AGS-EBV and AGS. ( a ) Two-dimensional score plot derived from the lipid profile based on the untargeted UPLC-QToF MS method showed marked differences between the AGS-EBV and AGS cell lines. ( b ) The heatmap showed distinguishable contrast regarding the expression of lipids.
Article Snippet: AGS is a human, female-origin,
Techniques: Expressing, Derivative Assay